Viagra professional: Top five myths about this popular drug

How Sildenafil Compares To Other ED Drugs Sildenafil, sold under the trade names Viagra and Revato, is a drug used primarily for the treatment of erectile dysfunction. It is the prototypical phosphodiesterase type V inhibitor, which has been of a significant help in saving the sex-life  of many that have suffered erectile dysfunction. Pharmacokinetics of Sildenafil Pharmacokinetics refers to what the body does to a drug. Sildenafil is administered both orally and parenterally as an intravenous bolus. It has a bioavailability of about 40%, and its plasma protein binding is about 96%. Its onset of action is within 20 to 30 minutes, and its pharmacological effects last for about 2 hours. It is metabolized by the the liver microsomal enzyme system majorly CYP3A4, and to some extent CYP2C9. Its metabolite N-desmethylsildenafil has an approximate potency of 50% for PDE5 receptors (phosphodiesterase type 5 receptors). The elimination half life for sildenafil is about 3 to 4 hours, and it is excreted largely in feces and a small portion is excreted in urine. The oral dosage form is sildenafil tablets available as viagra or revatio (both having different indicatons), whereas the intravenous formulation is a sildenafil salt, sildenafil citrate.  Mechanism of Action Generic Continue Reading

The Danger of Male Prostate Cancer: The Neglected Threat of Aging Males

Prostate Cancer In Australia Prostate cancer is one of the leading types of cancers affecting men in Australia and around the world. The prostate is a small gland located near the reproductive organs of men that both produces and transports seminal fluid. This gland is susceptible to cancer and there are several factors that can increase your risk of prostate cancer.  Risk factors Risk factors are things that can increase your chance of getting prostate cancer. some of the risk factors that men face when it comes to prostate cancer include age, a history of prostate cancer, exposure to certain chemicals, and diet. A research study on prostate cancer in veterans conducted in 2013 By the Portland VA Medical Center with the help of the Oregon Health and Science University discovered that veterans had an increased risk of having prostate cancer. Those who were exposed to the chemical agent orange not only have an increased risk of prostate cancer but they are more likely to get an aggressive form of cancer. How many cases a year American Cancer Society has recorded around 170000 cases of prostate cancer in the United States. Over 31,000 deaths occur as a result of some Continue Reading